Extreme heat and some medicines can be a risky duo [Video]

WASHINGTON — Extreme heat can raise the danger of heat-related illnesses and threaten health in a more subtle way — by amplifying the side effects of many common medications.

Hot weather, too, can damage medicines such as insulin that require refrigeration. Inhalers can explode. Epinephrine injectors such as EpiPens can malfunction. Meds delivered in the mail can deteriorate.

A look at common problems and solutions related to heat and medicine:

Which medicines could cause problems in the heat?

Blood pressure pills that reduce fluid in the blood can lead to dehydration. Beta blockers for heart conditions can decrease blood flow to the skin and make you less aware of dangerous heat.

Some antidepressants can hinder your ability to stay cool. Aspirin and other over-the-counter pain relievers decrease fluid and sodium levels, making it harder to deal with …