Australian and German researchers find cure for deadly skin disease ‘TEN’ [Video]

Researchers from Australia and Germany have for the first time cured patients suffering from toxic epidermal necrolysis (TEN), a deadly skin disease, said a news release on Monday.

An international collaboration, including researchers from the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne and the Max Planck Institute of Biochemistry in Germany, has developed the first-ever cure for TEN in a breakthrough study published in Nature, WEHI said in a news release on Monday.

Also known as Lyell’s syndrome, TEN is a rare skin disease that causes widespread blistering and detachment of the skin and can lead to dehydration, sepsis, pneumonia and organ failure, Xinhua news agency reported.

The potentially deadly condition is triggered by a severe adverse reaction to common medications and has a mortality rate of approximately 30 per cent.

The new study identified a hyperactivation of the JAK-STAT signaling pathway– a chain of interactions between proteins in a cell that is involved in processes …